Blue Flower

Below is series of medical research studies links from the National Institute of Health. The focus is on the impact of Cannabis & Cancer.  Most of these studies were done outside of United Stated due to the restrictive nature of NIDA and the DEA doing any studies that show a positive impact of cannabis for medical use.  At the end, there is a list of articles compiled by the International Association of Cannabis Medicine..

Studies on Cannabis & Tumor cells:

Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism 

The expression level of CB1 and CB2 receptors determines their efficacy at inducing apoptosis in astrocytomas 

In vivo effects of cannabinoids on macromolecular biosynthesis in Lewis lung carcinomas 

Cannabinoid receptor systems: therapeutic targets for tumour intervention 

Predominant CB2 receptor expression in endothelial cells of glioblastoma in humans 

Hypothesis: cannabinoid therapy for the treatment of gliomas 

Involvement of cannabinoids in cellular proliferation 

Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress-related genes 

Cannabinoids and gliomas 

Opposite changes in cannabinoid CB1 and CB2 receptor expression in human gliomas 

The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells 

The CB2 cannabinoid receptor signals apoptosis via ceramide-dependent activation of the mitochondrial intrinsic pathway 

Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. 

Down-regulation of tissue inhibitor of metalloproteinases-1 in gliomas: a new marker of cannabinoid antitumoral activity? 

Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines 

Endocannabinoids as emerging suppressors of angiogenesis and tumor invasion 

Cannabinoid receptors in human astroglial tumors 

Cannabinoids induce cancer cell proliferation via tumor necrosis factor alpha-converting enzyme (TACE/ADAM17)-mediated transactivation of the epidermal growth factor receptor 

Delta9-tetrahydrocannabinol inhibits cell cycle progression in human breast cancer cells through Cdc2 regulation 

Pharmacokinetics and pharmacodynamics of cannabinoids 

Cannabidiol inhibits angiogenesis by multiple mechanisms 

Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer 

The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells 

Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid 

For more studies and reports see International Association of Cannabis Medicine list of studies with links.  Note: some of the IACM links have a typo so the PublMed link is also included.